Quantum Effects in Electrochemical Biosensing Mediated by Nano-particles

***Archived: This is a past project,  it is not on offer at the moment!***

 

Introduction


There are number of biomolecules that have proven capabilities to process and store information within living beings. Some of the biomolecules which has attracted attention of researchers towards molecular electronics and sensors are proteins, neurons, lipids and Deoxyribonucleic acids (DNA). Proteins constitute most important class of biomolecules responsible for majority of biochemical reaction and information processing in all living species. Nanomaterials prepared from metals, semiconductors, carbon or polymeric species, in wide range of shapes ( solid particles, tubes , rods , ribbon , fibers , ropes etc)  and sizes ( less than 100 nm), have been widely investigated for their attractive electronic, optical, magnetic, thermal, mechanical and catalytic properties for their widespread applications. Owing to their unique properties, nanomaterials are of considerable interest in the nanosensor to achieve high sensitivity, selectivity , and stability  The performance characteristics of nanomaterials and biomolecules can be enhanced many folds for large number of applications by making their conjugates

The Master Project
In the present study large amount of data has been generated on cyclic voltammetery of 10 different types of nanoparticles under different conditions with three analytes . The results have been explained to a extent in terms of geometrical consideration , ligand length , quantum consideration .  High sensitivity for all the three molecules studied  indicates selective and sensitive  quantitative analysis can be achieved for  cyclophosphamide , etoposide and potassium ferrocynide.

 

Tasks:


  • Preparing nano-structured electrodes 

  • Acquiring electrochemical signals from the nano-structured electrodes
  • 
Computing the sensing performances obtained by nano-structuring
  • Developing a model describing the improved sensitivity



 

Requirements:

  • 
Basic knowledge on sensors
  • 
Basic Knowledge on nanotechnology
  • Experience with electrical measurements with lab equipments

  • Interest in quantum devices

 

This project was supervised by Sandro Carrara.

 

***Archived: This is a past project,  it is not on offer at the moment!***